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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f70a1647af4ea8404d1949dca86af587a99fd065ad83837882b13ae030f7fb36' 
  AND token = 'ICsM5law/LgEeViGtc9C9aPgmr22+LfavtgSh82kb8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}