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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a68801287a2fd8ab40d4a2fd86159495c39995c50911943a28070c0463cc929' 
  AND token = '+FWX/0T2zP/2/ZsA0PxkOYXJ+YSky2DYOyUtruI0uVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}