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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a46e91c53d5ce80287aa04320041ce7766c1376b6a2380539da1b3ebe8d5102' 
  AND token = '+s9MOrVqSWcNWlRoobp7uGux/jn7wCIsmDDUCP6L/1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}