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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27da9dc631f5bb58a903ec5246d05fd84eb45da8cfc359200972e71efb9f093' 
  AND token = 'W+PTLQTrS0nLjBIa3fGZMzUTmKwwZLuf13LkywNsEJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}