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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5049a9318a94c07403da9b745b1edf7aa04c01534dc3b7288f10e2f8450be952' 
  AND token = '1ngMo3B5ti3HdhzKdEaA6nWNOl5QrJ9ZHPsqJAm2OfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}