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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ceb54448087888710fea194d1794235e7626c23e61822656a4085e9073dcfb8' 
  AND token = 'tgHprVqD12Yn/PPTzUPl6rnUFZ15Rn6OXGcR+j3R0Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}