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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9da6bc0b5b6bf9f7646fa4af76a620524326181a1053beeafb1c9ba05722664c' 
  AND token = 'U+3E36wqI/xopzJsV5lTCgO4+kQPOLM0TkvAC6hWbpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}