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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a65b2b0f13bbf86923a4982489bdfe553b79b8d4309c76b01ce2507511cbb8' 
  AND token = 'FihNeU9JiVdWMmtMo8Ql7yXHstpn3/TWeCRdlr4lShU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}