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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '633065532d549bf33389e7403229ee95066a3eaaa539c5e22b9b87bdd860ccf4' 
  AND token = 'xx90M6Mwp80+5i9KOvw8ZFYffHEvLf/N7B6oFyoZIBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}