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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286c365894ef18283a3afcaa0c4c4f27e66214136fc852b90f49347746cd319a' 
  AND token = 'mSqFD3dqvBts8xGJr2UqvpGXg2mBkIej0k/y1csuQ/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}