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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09673cd22ec80e6831c2c8ec8ddff067f2087ba8b5b27015e07f271afa84a584' 
  AND token = '+Uqa+hXN9wcja4U6aiSWR96jp5M4RNjyXxwzAXYL71k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}