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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b410eab7931023ad8bcf344b1453e06e7dff3461a056cfe71c8b723b3d75fa50' 
  AND token = '+VVaejRNLef8/5+zeisabBgiHTAHJvctbQ7T2JA4jCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}