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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de6aeb0d83d6152d2c668d5846487c609e7218fff2298f6a9d862219b0ad138' 
  AND token = '+2KwFaqkiLDnARZqiaVHpH5Yze5LsXitHSZ21fBdDU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}