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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6574d6d3c75babcbf8a3b1d6bfbb789a18d0fb38077921cc857a48edd263502' 
  AND token = 'XLLS2IeIvH8/cyil1Xt3/8ntiZfgLcLFEUtFV+8KtNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}