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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fcfc8180b31644d7dd0ed8c089a7021b7733230e03edc23add3f60bbb5a744c' 
  AND token = 'iloAppUmmhmqAxhTZ45anl3IU7aCYtGDYd4Szq/7dQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}