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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e40d985df9c47602f267f6ba28e760ec71ecb6dfafdb35b6c5a910e8b517905f' 
  AND token = '6iiqVBXurRWgIqqiG9kl7kCXwBIGRiO4eRy8Ce7FGMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}