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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adb7c4bababc6d917b7a33204c6fffaaa36655a14bacf6b50cf54370a7a0aa4' 
  AND token = 'mUE/BdNAub72NMnIniZWn1F+0TCap2tPD6KZIvp2jmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}