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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db68b30d6936f9aae51e04b2c3d522b47750856901a659d21e56c42f47cc82b' 
  AND token = 'NkYpf6upbyw4K8oB6SDeVhlC++FSbxWFKtlrCOgoBQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}