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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d61306d59330a01f10ac4fb2d1aeacedf256b1b6683fd57b587fb124d8e0b5' 
  AND token = 'crC5e9pdVgwuHbR1R1ZHV6E/5flRsQe8pGk59//Sh3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}