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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b78540c9388305671cb579a1c177525cc04b7968451f93ca29c50a2433b95ca' 
  AND token = 'eeEsdtd9FGEmpd+WWzzhxhQ7Gq5uV4SFzJW8nFUvnos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}