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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d4b0f0acf4080f1654e352b03cdb80ada6b106c4a6e621112c4f4a204d1fa26' 
  AND token = 'nbi0mqSJY+BkGHQhDI1BwIHk9TLNXelfcXV+7Q56H/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}