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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4466a401449b9f6f9ac0f97b52e318cbdd54f191e8632624f0cdb48fed8b49' 
  AND token = 'k6lk0phxYQPK0hAgxmHA8yIuggqOz5r5bDV3klZH9IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}