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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8632fa8ec2ee9ec750ff01a9c6d1c21c94c1b830389b20821af733e57a69ce' 
  AND token = 'kn2HB25yRUjCJmvo6ZvJD9M/uDtYS9cmbHaK9XdyOe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}