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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a88a678ee76e12bdd9f046cc1158ac669bfc4183b6141a76a7bf252235222bd' 
  AND token = '3wPJ0BLd+QnMp5+6SkbAxCOIrU77k7UD2xOmFXzm3Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}