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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0959cb7080d5586d06da071021e0d7d63bc09849766e4b3d6b18566b98d191c' 
  AND token = 'bm1kfjga5Xbrp4cIlb9rdeibd3HSU6KTSiXEOa3BZoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}