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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e127f12b34f10004f96f32020f3bfc5b35f4d3fbd16dd3d8a9d805052cb41393' 
  AND token = 'MbZWMVcDrRbatfW5Me41ZEg+wmOl9sSNziFR9dVEWcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}