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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '912ad563b2691c4e95d95114a4cad17d1bec3e6b7ab6d00fbf4408fe04d97238' 
  AND token = 'HZTEmpQgz+pcuWdVa8zbpss8n3dAUcn4VYD1nWpIPdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}