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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ce5a1fa358772253608b3a494e42807675cb24efc81a18b5ac615684d3952f' 
  AND token = '6qBSxb8KUukR25ywypsdgfMRavC3YLInu/pMH62EsH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}