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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef4d9a3afd192283fb6715f2e1b5fe813ac8d59c757406bf75719712d992e66' 
  AND token = '6sISqn7G8A42Q3qEXQNbea1UKz5/HI7wACAfNdfCUfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}