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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f028a5203b75365c37d987450015d61c1c7e3ac51f7c3f47974b5394ac22561' 
  AND token = 'dxvAlMGGlLJ/gVJWvT6JexyVUcEXA7o0INmxIOm0rvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}