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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24d88313034a9d639dac70f23cabf1e1f6b69a38421addaa2edefe4ef94df204' 
  AND token = 'xe7Srw8+2E0eK8WxPbi0VygptZ1XTtRhu0/JkEERd8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}