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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d08489bd40e6296ab093410d25d40ea4bdc4af33c8f8d621b4259772f88cc36' 
  AND token = 'TwoOvTefLoiYGrJlbuJ4pwEG0JMUT+kPW5PTWwK7uTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}