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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c3c2dd9228a4326c45c2dc203cb95076c4538f504d635bd2ac1dfb6b06fa8b' 
  AND token = 'RrIyrIvOKl9MCrblKBkhW5KPXAWKwlPbeczc7XV22Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}