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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddf2997ef03aa11b5f8a81feda357848ec06659e252e59dc272050fe2770449' 
  AND token = '9GMzu8gIUaTvcWYP/FqviriKrkrRqc8aVRO1/Vfsijw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}