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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b2c025db5f9cdd1f2a74c22483dc5f1e5040405556f7cb42a8d922e88586d8' 
  AND token = 'Urd2zztDZdNyvFKVVTC9BqcjqBNyn2VjvdR/hHsaQOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}