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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b0846cbeb988c5b2d685ceeb80531ba1343d6f204c1bbdd371613b40e5c388' 
  AND token = 'HAWshk3twIAgxmt53NgJaaHNNNO62RxqU7uUYt0CXvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}