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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60eafded2bf8d7502346b85b7d3aae83578edfc08f442c8f894dc417da0723c1' 
  AND token = 'VvWAOpmx1j9XKiCnrif+BCapOHyG55ZBNiDjmfM4oG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}