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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f4f44463b61a82e29d6dfe9e9bd46955992e0697054e6aa6d2b2aacd482504' 
  AND token = '1xbwHu9jiQWJZ+66fYJhgeqN657IsyGH8PEl+ukc0Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}