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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8692e15475c17ec0ce52c2bf52aa80116ec2d0e4cf7d967f16efadd26bf90d' 
  AND token = '9pAIwqW8jrsrlxRwLnP1PT1u9ZdIhFfJgdjmKF0PRCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}