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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8590937c60e592be5b9404b8bd8be4b6e29f4cdee289b56a196d5b0bac1a74a1' 
  AND token = 'vD2zl0oSVIC67IFPl5QRB1V0j4uPlLXlth37m2ehC2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}