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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b361820c758d3e8bb138910092da3a773acd43c2bcb38c9629a1332b38cb9f40' 
  AND token = 'l1z2r3FzU/KNMkeZxzPEH4aC4Dz3jj1ui11CxrrRKkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}