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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4b4ecebb114f0bca51d41fb1084d562159c12d6054605813b7e987e5a76465' 
  AND token = 'JwE/kOxfI0vqdvX0RWKleeoIM6CsxNOE4pYtuB/h3ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}