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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185e4ad5b8ce060e5e39e8fea421351909df06dc09e123b84e2ba73e07cf150c' 
  AND token = 'R2lhBHmCeuGKXgVokhsHuNDe/Q2jUCr4iGr0ql+xDtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}