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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58125588dac0b49e606ea42c7a5f78af5cebc4e6074303737e23223c44cb0529' 
  AND token = 'TXGsuFd/kCpeurHSLEXcACO9dEkkvSKDsAcuNYXrQWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}