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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6b15d9198a58f675d8c38d21ac9d99c2b11ccb16f598a1cea469e5a79ff260' 
  AND token = 'B5im6CGyVzgFShELA9MFfnW/usgM7Cfib4JLgcgxuy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}