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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1dbd7eb5d187ca1935f1646368009350442ce933e6658723e09ec03f0b8251e' 
  AND token = 'VRO6gQ5TO8y8NPlkJl8cV4+dQAM/LEHGJpc9niEtKlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}