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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b35364a0c7f0f0102bced301292b7896d3c1ac0bbe7aefd25a3c3b3562ef5ea6' 
  AND token = 'YXnfywqo52FpmZEsUQdsffup+bWpNs0SMGbhsW4bRqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}