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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc81f1abf0eb64fc2fbf0eb8637a1595f80274887de198921a27659b42ab6f27' 
  AND token = 'bIyL9vD3K1YoiUpxnskh6yY7WTpP46/xRNRR4mxff5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}