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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfd40f6ae75e62e3a53f94656d00f8f9e61385438078be5a31d7ed4774d71a90' 
  AND token = 'OF5mcgnv/QsiOwRfVsqaQVCFuLA+egEgust9X7tCrUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}