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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66f2cdd319e10a95d2d7fcdb6b5d3d45d7cf217f223800858da53b2482c3fe0' 
  AND token = '4tBcamnz1IMkhMsVGRyuRcD8C13LVnf7dJEFXI2hgm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}